High Dose Niacin Benefits For Depression & High Cholesterol

March 31, 2017

I first heard about niacin (Vitamin B-3) when I did a wellnessfx blood test four years ago.

The health practitioner told me about niacin to reduce my very high cholesterol. I then proceeded to buy and take a 100mg tablet and freaked out because my whole skin felt like it was on fire a few minutes later. I emailed her late at night to find out what the heck was happening and if it was dangerous!

That started my research, experiments, and love of this super cheap vitamin.

Nowadays I take 1g of niacin three times, totaling 3g a day. This is what I heard Andrew Saul takes. And I thoroughly enjoy the warm “niacin flush” and even look forward to it these days.

Niacin Benefits:
The main benefit of niacin is to lower cholesterol.
And it works beautifully as I found out through my blood test results.

I read that niacin was used by Bill Wilson, cofounder of Alcoholics Anonymous, to treat alcoholics.

Niacin is also helpful for depression, because it affects serotonin production in the body.

What happens is that the amino acid tryptophan we get from food is used by the body to create niacin and serotonin. If we’re deficient in niacin, body will use tryptophan to make that rather than serotonin. So when we take niacin, body will start to use that tryptophan to make serotonin. At least that’s what I’ve read and experience from personal mood lifting.

Nowadays, my supplement routine is to take fish oil, 5htp, vitamin d, b complex, and niacin for depression and mood issues, along with a diet plenty of plants (fruits, veggies, grains, tubers). I also avoid the bad stuff of course (dairy, wheat, processed food, alcohol, etc). This is helping a lot and I feel great.

It’s important to take the regular niacin (nicotinic acid) and not the “no flush niacin” which I read can be harmful for the liver. And don’t take niacinamide either, which I think is a synthetic form of niacin and does not have the same mood lifting benefits.

If you’re on medication or have other health issues, it would be wise to research if niacin interferes with that. Niacin is a blood thinner, so you don’t want to take it if you’re on blood thinning medication.


Niacin: The Real Story – book
The Many Benefits of Niacin
Niacin Adventures: Part 1 – Nature’s Prozac

Niacin Therapy Details

The term vitamin B-3 was reintroduced by my friend Bill W., co-founder of Alcoholics Anonymous, (Bill Wilson). We met in New York in 1960. Humphry Osmond and I introduced him to the concept of mega vitamin therapy. We described the results we had seen with our schizophrenic patients, some of whom were also alcoholic. We also told him about its many other properties. It was therapeutic for arthritis, for some cases of senility and it lowered cholesterol levels.

Bill was very curious about it and began to take niacin, 3 g daily. Within a few weeks fatigue and depression which had plagued him for years were gone. He gave it to 30 of his close friends in AA and persuaded them to try it. Within 6 months he was convinced that it would be very helpful to alcoholics. Of the thirty, 10 were free of anxiety, tension and depression in one month. Another 10 were well in two months.

How to determine a saturation level for niacin

Says Dr. Hoffer: “A person’s “upper limit is that amount which causes nausea, and, if not reduced, vomiting. The dose should never be allowed to remain at this upper limit. The usual dose range is 3,000 to 9,000 milligrams daily divided into three doses, but occasionally some patients may need more. The toxic dose for dogs is about 5,000 milligrams per 2.2 pounds (1 kilogram) body weight. We do not know the toxic dose for humans since niacin has never killed anyone.”

Niacin 500mg tabs – the type I take, super cheap and lasts forever.